Medical sutures are key materials used to close tissues during surgical operations. The preparation of their surface coatings aims to optimize performance (such as lubricity, biocompatibility, antibacterial properties, degradation regulation, etc.) to reduce postoperative complications (such as infection, tissue adhesion) and improve clinical outcomes.
The design of the coating needs to be based on the clinical needs of the suture, core functions and corresponding requirements:
● Lubricity: Reduce tissue damage during suturing (reduce needle resistance), the coating surface friction coefficient needs to be low, and it needs to be stable in a moist environment (body fluid).
● Biocompatibility: Avoid triggering immune response or toxicity.
● Antibacterial: Inhibit bacterial growth at the suture site (such as Staphylococcus aureus, Escherichia coli), long-term antibacterial and no risk of drug resistance.
● Degradation regulation: Match the degradation rate of the suture substrate (absorbable sutures need to degrade synchronously, and non-absorbable sutures need a stable coating).
● Healing promotion: Accelerate tissue repair by loading growth factors (such as VEGF) or natural active ingredients (such as hyaluronic acid).
Ultrasonic spraying technology is a precision coating preparation technology that uses ultrasonic vibration to achieve precise atomization and deposition of solutions. It has significant advantages in the preparation of functionalized coatings on the surface of medical sutures. The core feature is that the ultrasonic transducer converts electrical energy into high-frequency mechanical vibrations, so that the solution is atomized into uniform droplets of micrometers or even nanometers under the action of vibration energy, and then deposited on the surface of the suture through drainage and air conduction to form a thin and uniform coating. It can accurately cover the slender surface of the suture (including surface texture, pores, etc.), avoiding the "local accumulation" or "missing coating" problems in traditional methods, and ensuring that the coating thickness deviation can be controlled within ±5%.
With its characteristics of "high precision, low damage and high utilization rate", ultrasonic spraying technology has become one of the core technologies for the preparation of functional coatings in the medical field, especially in the fields of precision medicine, personalized implants, and interventional fields, and has broad application prospects.
