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Drug balloon coating technology -- Ultrasonic atomization -- YMUS ultrasonic spraying
Drug coated balloon (DCB) is a new type of coronary interventional therapy technique in recent years, which was first used to treat stent restenosis. The surface of the DCB is evenly coated with anti-cell proliferation drugs (paclitaxel or rapamycin). As the balloon expands, the drugs quickly enter the vascular wall tissue and remain there for 7-14 days, acting as a treatment for restenosis in the stent without the need for a new stent.
The balloon can be atomized by ultrasonic coating, uniform deposition of anti-restenosis drug film onto the surface. YMUS Ultrasonic Precision Spraying equipment applies a thinner, more uniform, and more efficient coating of medical solution to the balloon.
Note:Drug balloon catheter
Benefits of ultrasonic spraying on balloon catheter:
● Highly uniform film coating on balloon catheter for uniform drug transfer
● Compared with dip coating can significantly save material
● Reliable, repeatable and controllable balloon catheter coating
● Can atomize common chemical combinations, including hydrophilic carriers and plasticizers, to increase the flexibility of the coating
● The durable coating does not crack or flake, ensuring proper delivery of medication at the blocked site
Note:Ultrasonic atomizing nozzle
Ultrasonic nozzle technology
The ultrasonic nozzle is composed of a liquid inlet part, a connecting controller part, a transducer and a nozzle. The ultrasonic nozzle partially converts high-frequency electrical energy into mechanical energy through the transducer, which is transferred to the liquid to produce standing waves. As the liquid leaves the atomized surface of the nozzle, it is broken into a fine mist of uniform micron sized droplets.
YMUS-DG300 Ultrasonic spraying system
Equipment characteristics
◆ Balloon catheter spraying: integrated sprinkler head, ultrasonic control, liquid conveying, balloon catheter loading and unloading blowing drying and movement system;
◆ High uniformity of drug coating, drug coating without adhesion pinhole orange peel and other defects;
◆ Support various specifications of balloon coating;
◆ Suitable for balloon maximum length: 300mm;
◆ Suitable for peripheral support specifications: usually the length is not more than 280mm, diameter is not more than 60mm;
◆ Conversion efficiency of drug coating is 4-5 times higher than that of pneumatic spraying;
◆ Unique bracket fixture design: fast loading and unloading bracket;
◆ XYZ three-axis stepper motor sprinkler motion system, double-stepper motor catheter balloon rotation system;
◆ Can expand a variety of medical equipment spraying: such as stent, catheter, guide wire, etc. (single fixture and tooling)