An emerging thin film preparation technology shows great application potential in the field of medical drug coatings.

Medical drug coating, thin film preparation - ultrasonic spraying

Medical drug coating refers to combining drugs with polymer materials and coating them on the surface of medical devices through specific process technology to achieve the purpose of treating diseases, preventing infections, promoting tissue repair, etc. Traditional drug coating preparation methods such as dipping and spraying have problems such as poor coating uniformity, low drug utilization rate, and complex process. The emergence of Shanghai Yangmi ultrasonic spraying technology provides a new solution for the preparation of medical drug coatings.

Working principle of ultrasonic spraying equipment

Ultrasonic spraying equipment is mainly composed of ultrasonic power supply, ultrasonic atomization nozzle and liquid supply system. Its working principle is to use the high-frequency vibration of ultrasound to break the liquid drug solution or suspension into micron-level or even nano-level droplets, and then spray the solution onto the surface of the substrate through the carrier gas to form a uniform film.

Compared with traditional drug coating preparation methods, ultrasonic spraying equipment has the following advantages:

1. Good coating uniformity: The droplets produced by ultrasonic spraying are small in size and evenly distributed, which can form a dense and uniform drug coating, improving the release efficiency and therapeutic effect of the drug.

2. High drug utilization rate: Ultrasonic spraying can deposit drugs directly in the target area, reduce drug waste, and improve drug utilization rate.

3. Strong process controllability: By adjusting parameters such as ultrasonic frequency, power, and atomizing gas flow, the thickness, morphology, and drug release rate of the coating can be accurately controlled.

4. Wide range of applications: Ultrasonic spraying technology is suitable for various types of drugs and polymer materials, and can prepare medical drug coatings with multiple functions.

Examples of the application of ultrasonic spraying equipment in the preparation of medical drug coatings include: drug eluting stent coatings, antibacterial coatings, tissue engineering stent coatings, drug balloon catheters, medical guidewires, etc.

As an emerging thin film preparation technology, ultrasonic spraying technology has broad application prospects in the field of medical drug coatings. With the continuous development and improvement of technology, ultrasonic spraying equipment will play an increasingly important role in the medical field and make greater contributions to human health.