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Medical grade TPU solution to prepare precision coating - ultrasonic spraying
Medical-grade TPU (thermoplastic polyurethane elastomer) solutions are widely used in the medical field:
● Catheter coating: such as urinary catheters, vascular catheters, etc., TPU solution can be coated on the surface of the catheter to enhance lubricity, make catheter insertion smoother, reduce damage to human tissue, and improve biocompatibility, reduce infection risks and body rejection reactions.
● Medical tubing: used to manufacture medical-grade tubing, such as endotracheal intubation, nasogastric tubes, etc. The tubing processed by TPU solution has good flexibility, tear resistance and chemical resistance, and can adapt to different use environments and operating requirements.
● Drug-coated stents: In cardiovascular interventional treatment, coating the drug-containing TPU solution on the surface of the vascular stent can achieve slow release of drugs, inhibit the proliferation of vascular smooth muscle cells, prevent vascular restenosis, and improve the therapeutic effect of stent implantation.
● Implantable drug release devices: such as implantable micropumps and microspheres used to treat cancer, neurological diseases, etc. The carrier made of TPU solution can accurately control the drug release rate and dosage, prolong the drug action time, reduce the frequency of drug administration, and improve patient compliance.
● Biosensors: In the preparation of biosensors, TPU solution can be used as a sensitive membrane or packaging material to fix biological recognition elements such as enzymes and antibodies, while protecting the internal structure of the sensor, improving the stability and service life of the sensor, and realizing rapid and accurate detection of biological molecules and physiological indicators.
How should the coatings on the surfaces of these medical device consumables be prepared more uniformly and precisely? Shanghai Yangmi's ultrasonic spraying technology perfectly solves the problem of this process.
Advantages of ultrasonic spraying technology:
● High uniformity: The droplets produced by ultrasonic spraying are small in size and evenly distributed, which can form a dense and uniform coating on the surface of flat surfaces and pipes, avoiding the problems of uneven thickness, dripping, and missing coating that may occur in traditional spraying, and can make the coating uniformity reach more than 95%.
● Strong adhesion: The vibration of ultrasound allows the solution to better contact and combine with the product surface, greatly improving the adhesion of the coating and ensuring that it is not easy to fall off or peel off during use.
● Accurate thickness: By adjusting the parameters of ultrasonic spraying, such as spraying time, liquid supply flow, ultrasonic nozzle frequency, etc., the thickness of the coating can be accurately controlled to meet the strict requirements of coating thickness for different medical applications.